Receptor D₅ de dopamina

DRD5
Identificadores
Nomes alternativos	DRD5
IDs externos	OMIM: 126453 HomoloGene: 20216 GeneCards: DRD5
Doenças Geneticamente Relacionadas
	blefaroespasmo
Targeted by Drug
	A-68930, serotonina, beta-ergocriptine, bromocriptina, cabergolina, dopamina, pergolide, Rotigotina, apomorfina, lisurida, SKF-38393, (+)-butaclamol, clorpromazina, clozapina, ecopipam, Flupentixol, flufenazina, haloperidol, cetanserina, SCH-23390, espiperona, thioridazine, tavapadon, pimozida, pergolide mesylate
Ontologia genética
Função molecular	• G protein-coupled receptor activity; • dopamine neurotransmitter receptor activity; • signal transducer activity; • dopamine binding; • dopamine neurotransmitter receptor activity, coupled via Gs; • G-protein alpha-subunit binding;
Componente celular	• integral component of membrane; • membrane; • membrana plasmática; • integral component of plasma membrane; • brush border membrane; • ciliary membrane; • non-motile cilium; • intracellular anatomical structure; • cílio;
Processo biológico	• response to cocaine; • cellular response to catecholamine stimulus; • regulation of female receptivity; • sensitization; • adenylate cyclase-activating dopamine receptor signaling pathway; • associative learning; • adenylate cyclase-activating G protein-coupled receptor signaling pathway; • norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; • negative regulation of blood pressure; • transmission of nerve impulse; • response to amphetamine; • regulation of systemic arterial blood pressure by vasopressin; • cicatrização de feridas; • cellular calcium ion homeostasis; • mating behavior; • aprendizagem; • negative regulation of NAD(P)H oxidase activity; • activation of adenylate cyclase activity; • reactive oxygen species metabolic process; • phospholipase C-activating dopamine receptor signaling pathway; • Depressão de longa duração; • GO:0072468 transdução de sinal; • chemical synaptic transmission; • synaptic transmission, dopaminergic; • G protein-coupled receptor signaling pathway; • positive regulation of adenylate cyclase activity;
	Sources:Amigo / QuickGO
Padrão de expressão RNA
	Mais dados de referência de expressão
Ortólogos
	1816
	n/a
	ENSG00000169676
	n/a
	P21918
	n/a
	NM_000798
	n/a
	NP_000789
	n/a
	Wikidata
Ver/Editar Humano

O receptor D₅ de dopamina, também conhecido como D5R, é uma proteína que, em seres humanos é codificada pelo gene DRD5. Funciona como um receptor acoplado à proteína G.